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Denervation in the primary olfactory pathway of mice. III. Effect on enzymes of carnosine metabolism

Harding J, Margolis FL. Brain Research, 1976; 110(2):351-360.

Laboratory studyOther animals

Design
Laboratory study
What was measured
Carnosine synthetase and carnosinase activities in the mouse primary olfactory pathway after peripheral deafferentation or central denervation.

What the authors reported

Carnosine synthetase activity in the mouse primary olfactory pathway exceeded that of other tissues and brain regions, while carnosinase was high only in the olfactory epithelium. Peripheral deafferentation or central denervation selectively reduced carnosine synthetase in the reciprocal part of the pathway, implying localisation within receptor neurons and supporting a role for carnosine in olfactory transmission.

Limits of this study

Mouse neurochemistry. Abstract only.

Source

PubMed 938948 · doi:10.1016/0006-8993(76)90407-8

Entry checked against PubMed abstract (E-utilities) on 2026-10-19. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.