Chicken Breast Attenuates High-Intensity-Exercise-Induced Decrease in Rat Sarcoplasmic Reticulum Ca2+ Handling
Controlled trialOther animalsWith chicken breast extract (carnosine and anserine source)
This study tested carnosine together with chicken breast extract (carnosine and anserine source). Its results cannot be assigned to carnosine alone. More combination studies.
- Design
- Controlled trial
- Dose used in the study
- diet containing chicken breast extract
- Duration
- 5 weeks
- What was measured
- Muscle carnosine and anserine; sarcoplasmic reticulum calcium handling after a 2.5 min high-intensity run in rats.
What the authors reported
Five weeks of chicken breast extract raised rat muscle carnosine by about 15% and anserine by about 45% (p < 0.01). In resting muscle it lowered sarcoplasmic reticulum Ca2+-ATPase activity without changing Ca2+ uptake and release rates. After high-intensity running, sarcoplasmic reticulum Ca2+ handling fell less in extract-fed rats than in standard-chow rats (p < 0.05). The extract is a source of histidine-containing dipeptides generally, not carnosine alone.
Limits of this study
Group sizes not stated in abstract. Rodents lack serum carnosinase, so oral results do not carry over to people. Full text not read.
Source
PubMed 18708689 · doi:10.1123/ijsnem.18.4.399
Entry checked against PubMed abstract (E-utilities) on 2026-10-19. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.