Regional and subcellular distribution of homocarnosine-carnosine synthetase in the central nervous system of rats
Laboratory studyOther animals
- Design
- Laboratory study
- What was measured
- Homocarnosine-carnosine synthetase and carnosinase activity across nine rat CNS regions and subcellular fractions; Km values for beta-alanine and GABA.
What the authors reported
Olfactory bulbs had the highest activity of both synthetase and carnosinase. Synthetase was mainly in the cell sap and carnosinase highest in mitochondria. Synthetases from olfactory bulb, cerebellum and spinal cord showed similar Km values for beta-alanine and GABA.
Limits of this study
Rat tissue enzymology. Full text not read. PubMed record carries no abstract, so findings could not be rechecked against PubMed; PubMed prints the page range as I87-90.
Source
PubMed 621500 · doi:10.1111/j.1471-4159.1978.tb07051.x
Entry checked against PubMed record (title and citation only, no abstract); findings from OpenAlex abstract on 2026-10-19. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.