Carnosine interaction with nitric oxide and astroglial cell protection
Laboratory studyOther animals
- Design
- Laboratory study
- What was measured
- Cell death and nitric oxide in primary rat astroglial cultures treated with lipopolysaccharide and interferon-gamma; nitric oxide and free radical scavenging in cell-free systems.
What the authors reported
Carnosine protected astroglial cells from nitric oxide-mediated death. Its nitric oxide scavenging correlated with its free radical scavenging, and cell-free experiments confirmed a direct interaction. Among related compounds only histidine showed comparable nitric oxide trapping.
Limits of this study
Cell culture; concentrations not stated in abstract. Full text not read.
Source
PubMed 17546663 · doi:10.1002/jnr.21365
Entry checked against PubMed abstract (E-utilities) on 2026-10-19. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.