Plasma carnosine concentration: diurnal variation and effects of age, exercise and muscle damage
Observational studyHorses
- Design
- Observational study
- Subjects
- not stated in the abstract
- Dose used in the study
- not applicable (no supplement given)
- Duration
- not stated
- What was measured
- Plasma carnosine in Thoroughbreds by age group, before and after intense exercise, within the day in fed and fasting horses, and during exertional rhabdomyolysis; relationship to creatine kinase and aspartate aminotransferase.
What the authors reported
The authors report that carnosine is detectable in horse plasma, which they link to the absence of plasma carnosinase in horses. Horses aged 3 and over had about 11.3 to 14.1 micromol/L; foals and yearlings about 3.9 to 8.7 micromol/L. Intense exercise raised plasma carnosine from 10.3 plus or minus 1.0 to 12.4 plus or minus 4.4 micromol/L (P<0.05). Exertional rhabdomyolysis produced 57.6 to 702.3 micromol/L. Higher values went with raised CK and AST but did not follow clinical severity.
Limits of this study
Sample size and diurnal results not in the abstract. No correlation coefficient given for the CK and AST relationship. Wiley page could not be loaded; abstract taken from a secondary index.
Source
doi:10.1111/j.2042-3306.2002.tb05434.x
Entry checked against abstract (Mad Barn research index); DOI and title confirmed by Wiley search listing; also cited in Harris et al. 2012 Amino Acids review on 2026-10-11. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.