Metabolic health
Published human trials in prediabetes, obesity and type 2 diabetes that measured glucose, insulin, lipids or body composition.
This page lists published studies. It reports what the authors did and found, with the limits of each study. It is not advice.
28 studies listed, newest first.
- Carnosine supplementation improves glucose control in adults with pre-diabetes and type 2 diabetes: A randomised controlled trialRandomised controlled trialHumans
- Carnosine Did Not Affect Vascular and Metabolic Outcomes in Patients with Prediabetes and Type 2 Diabetes: A 14-Week Randomized Controlled TrialRandomised controlled trialHumans
- Carnosine, small but mighty: prospect of use as functional ingredient for functional food formulationReviewHumansOther animals
- Effect of Carnosine or beta-Alanine Supplementation on Markers of Glycemic Control and Insulin Resistance in Humans and Animals: A Systematic Review and Meta-analysisMeta-analysisHumansWith beta-alanine (carnosine precursor) included alongside carnosine
- Histidine-containing dipeptides reduce central obesity and improve glycaemic outcomes: A systematic review and meta-analysis of randomized controlled trialsMeta-analysisHumansWith histidine-containing dipeptides (carnosine, anserine, beta-alanine studies pooled)
- Carnosine in health and diseaseReviewHumansOther animals
- The effect of 12 weeks carnosine supplementation on renal functional integrity and oxidative stress in pediatric patients with diabetic nephropathy: a randomized placebo-controlled trialRandomised controlled trialHumansWith ACE inhibitor (both groups, background therapy)
- l-Carnosine supplementation attenuated fasting glucose, triglycerides, advanced glycation end products, and tumor necrosis factor-alpha levels in patients with type 2 diabetes: a double-blind placebo-controlled randomized clinical trialRandomised controlled trialHumans
- Effects of carnosine supplementation on glucose metabolism: Pilot clinical trialRandomised controlled trialHumans
- Physiology and pathophysiology of carnosineReviewHumansOther animals
- The influence of a single nucleotide polymorphism within CNDP1 on susceptibility to diabetic nephropathy in Japanese women with type 2 diabetesObservational studyHumans
- Low plasma carnosinase activity promotes carnosinemia after carnosine ingestion in humansOpen-label, no control groupHumans
- Common variants in CNDP1 and CNDP2, and risk of nephropathy in type 2 diabetesObservational studyHumans
- Effect of anserine ingestion on hyperglycemia and the autonomic nerves in rats and humansControlled trialHumansOther animalsWith anserine (carnosine analogue, tested alone)
- Association Between CNDP1 Genotype and Diabetic Nephropathy Is Sex SpecificObservational studyHumans
- N-Glycosylation of Carnosinase Influences Protein Secretion and Enzyme Activity: Implications for HyperglycemiaLaboratory studyHumansOther animals
- Profiling histidine dipeptides in plasma and urine after ingesting beef, chicken or chicken broth in humansOpen-label, no control groupHumans
- Carnosine and its possible roles in nutrition and healthReviewOther animalsHumans
- The influence of carnosinase gene polymorphisms on diabetic nephropathy risk in African-AmericansObservational studyHumans
- A leucine repeat in the carnosinase gene CNDP1 is associated with diabetic end-stage renal disease in European AmericansObservational studyHumans
- Glycation, ageing and carnosine: are carnivorous diets beneficial?ReviewHumans
- Carnosine as a protective factor in diabetic nephropathy: association with a leucine repeat of the carnosinase gene CNDP1Observational studyHumansOther animals
- Quantitation of carnosine in humans plasma after dietary consumption of beefOpen-label, no control groupHumans
- Carnosine, a protective, anti-ageing peptide?ReviewOther animalsHumans
- Decreased activity of carnosinase in serum of patients with chronic liver disordersObservational studyHumans
- Homocarnosinosis: influence of dietary restriction of histidineCase seriesHumans
- Fluorometric Assay of Human Serum Carnosinase Activity in Normal Children, Adults and Patients with MyopathyObservational studyHumans
- Carnosinemia: a new metabolic disorder associated with neurologic disease and mental defectCase seriesHumans